Radical Simplicity

+ Resistance to first-line anti-malarial treatment raises concerns

Targeting C–H for Total Synthesis

+ The science behind why wet dogs shake

100-Year-Old Rule Broken

+ Early-life exposure to sugar increases risk of diabetes & hypertension

Programmable Polysubstitution

+ New retraction service casts a watchful eye over "high-risk" publications

A Carbon-to-Nitrogen Atom Swap

+ Molecular "dimmer switch" precisely controls blood glucose levels

Cracking Cyclopropane

+ AlphaFold earns a Nobel Prize 5× faster than average

Furan → Pyrrole

+ Lighting the way towards a new treatment for Alzheimer's disease

Phosphorus-Promoted Photochemistry

+ Reprogrammed stem cells offer hope as a cure for type I diabetes

Cross-(−CO)upling

News: a rise in antimicrobial resistance could mean 40 million deaths by 2050

Memory of Chirality

Plus news of "DIY pharmaceuticals" raises concerns

Enabling Etherification

Fluorine in Flow